Models of hepatitis C suggest that screening groups that are at risk of contracting the disease could limit suffering and health care costs, scientists report. The research has found that targeting at-risk groups for screening could significantly reduce disease progression, which eventually necessitates a liver transplant. Researchers at the University of Cincinnati have found that… [Continue Reading]
Targeted Screening of At-Risk Groups for Hepatitis C Could Help Control Disease Spread
Interferon Treatment Not Effective for Relapsed Hepatitis C Patients: Study
Hepatitis C remains difficult to treat, and in patients that don’t improve with first-line treatments, doctors sometimes resort to a therapy called interferon monotherapy. According to a new study however, this treatment comes with significant side effects and does not improve patient outcomes. People with hepatitis C and chronic liver disease who relapsed or failed… [Continue Reading]
Antibody Against Hepatitis C Effective in Animal Models
A potential new treatment to hepatitis C is effective in chimpanzee models of the disease, according to a new study. Hepatitis C is highly resistant to treatment, and circulating virus can reinfect patients after a liver transplant. Researchers hope that the new antibody could block reinfection, improving outcomes for transplant patients. A monoclonal antibody developed… [Continue Reading]
Green Tea Compound Fights Hepatitis C Infection of Liver Cells in the Lab
A compound found in green tea can block the hepatitis C virus from infection liver cells in the lab, a new study reports. The substance, called epigallocatechin-3-gallate, researchers suggest, could be used as part of a strategy to prevent liver infection after liver transplants in patients. German researchers have determined that epigallocatechin-3-gallate (EGCG)—a flavonoid found… [Continue Reading]
New Anti-Hepatitis C Antibody Helps Supress Virus After Liver Transplant
Advances in hepatitis research have allowed the development of a tool to push back the virus after liver transplant surgery, a new study reports. Suppressing the virus is a key goal of researchers, as even after liver transplants, active virus in the blood can infect the new liver. The researchers are now testing combination therapies… [Continue Reading]
Many Hepatitis C Patients Fail to Follow Their Treatment Regimen
The treatment protocol for hepatitis C can be complex, and a new study shows that many patients have trouble taking their medications according to their doctor’s instructions. Some pills have to be taken every 8 hours, and researchers say that developing tools to help patients follow their treatment regimen could make a big difference in… [Continue Reading]
Hepatitis C Vaccine Developed: Effective in Mouse Models
Hepatitis C is a virus of the liver that is spread by blood or body fluid contact, including shared needles, poorly screen blood transfusions, and sexual activity. The virus mutates so quickly, until now, it has been difficult to design an effective vaccine. Researchers have reported this week the development of an effective vaccine in… [Continue Reading]
Genetic Variants Linked to Protection from Anemia in Hepatitis C Patients
Treatment for hepatitis C can trigger anemia in some patients, and devising a way to predict who will be affected, and how to best treat them is essential to cure the disease. A new study has found that specific genetic changes are linked to resistance to anemia during treatment. The work may lead to the… [Continue Reading]
New Research on How Hepatitis C Virus Replicates Lays Groundwork for Future Therapies
Hepatitis C virus affects hundreds of millions of people around the world, and can lead to scarring of the liver and liver cancer. Current treatments are limited, but new research has gained new insights into how the virus replicates. Researchers have shown that one of the viral proteins interacts with another protein essential for replication… [Continue Reading]