Researchers have found that a compound called NIC5-15 could be a safe and effective treatment to stabilize cognitive performance in patients with mild to moderate Alzheimer’s disease.
NIC5-15 is found naturally in pine tree bark and many foods and is commercially available as an approved food supplement. It is believed to have the potential to prevent or slow the progression of Alzheimer’s disease
Early evidence suggests that NIC5-15 is a safe and tolerable natural compound that could reduce the progression of Alzheimer’s disease related dementia by preventing the formation of beta-amyloid plaque, a waxy substance that accumulates between brain cells and impacts cognitive function. .
“With Alzheimer’s disease affecting 5.2 million Americans, another 5 million with early-state Alzheimer’s disease, and nearly a half million new cases of Alzheimer’s reported annually, treatments like NIC5-15 would make a significant difference in the lives of many Alzheimer’s patients,” said Dr. Giulio Maria Pasinetti, study author. “We are hopeful that the follow up clinical study will support this preliminary evidence.”
“There are no FDA-approved Alzheimer’s disease modifying drugs available today,” said Dr. Hillel Grossman, study co-author. “Current drugs approved for use help maintain cognitive function, but only for a limited time. NIC5-15 is part of a new class of natural compound we found to have the potential of precluding the generation of ?-amyloid and, eventually, attenuating cognitive deterioration in preclinical models of Alzheimer’s disease.”
References:
1. Giulio Maria Pasinetti, et al. The Mount Sinai Medical Center.
