- Women with Atypical Hyperplasia Have a Higher Risk of Breast Cancer
- Mastectomy Patients Most Satisfied with Breast Reconstruction Using Their Own Tissues
- Follow Up for Breast Cancer Patients
- Helping Breast Cancer Patients Adhere to Hormone Therapy
- Opportunities Identified that Reduce Breast Cancer Screening Patient Burden
- Certain Birth Control Pills May Increase Cancer Risk
- Writing May Help Cancer Survivors
- New Method May Allow Breast Cancer Drug to Be Given Through Skin
- Findings Raise Hope of Preventing Breast Cancer with Statins
- Avoiding a Second Biopsy for Breast Cancer Patients
Study Explores How Sleep Deprivation Increases Risk of Migraine
Paul L. Dunham and his team sought to understand the mechanisms by which sleep disturbance increases the risk of migraine and may even trigger migraine.
“Previous clinical data support a relationship between sleep quality and migraine,” said Dr. Durham, “so we used an established model of sleep deprivation to measure levels of proteins that lower the activation threshold of peripheral and central nerves involved in pain transmission during migraine. We found that REM sleep deprivation caused increased expression of the proteins p38, PKA, and P2X3, which are known to play an important role in initiating and sustaining chronic pain.”
“So little is known about the biological mechanisms that underlie how certain factors trigger a migraine attack,” said David Dodick, president of the American Headache Society. “This is important work and this Missouri State team should be applauded for beginning to shed light on an area desperately in need of investigation.”
1. Paul L. Dunham, et al. American Headache Society.