Mouse Fat Cells Reprogrammed Into Clinically Useful Stem Cells

Scientists have “reprogrammed” adult mouse fat cells and neural cells to become stem cells that can differentiate into a variety of different cells (pluripotency). The cells, called “induced pluripotent stem cells” (iPS), are nearly identical to the naturally occurring pluripotent stems cells, such as embryonic stem cells, which are highly pluripotent, in short supply and… [Continue Reading]

Reprogrammed Stem Cells Do Not Completely Let Go of Their Past

According to researchers, adult cells that have been reprogrammed into induced pluripotent stem cells (iPS cells) do not completely let go of their past, perhaps limiting their ability to function as a less controversial alternative to embryonic stem cells for basic research and cell replacement therapies. The findings highlight a major challenge in developing clinical… [Continue Reading]

New Stem Cell That Can Be Easier Manipulated Than Current Stem Cells

Researchers from the Massachusetts General Hospital Center for Regenerative Medicine (MGH-CRM) and the Harvard Stem Cell Institute have a developed a new type of human pluripotent stem cell that can be manipulated more readily than currently available stem cells.

A Step Closer in Overcoming Induced Pluripotent Stem Cell Limitations

Scientists may be one step closer to being able to generate any type of cells and tissues from a patient’s own cells. Investigators describe finding that an important cluster of genes is inactivated in induced pluripotent stem cells that do not have the full development potential of embryonic stem cells.